Mitchell Chesler

Postdoctoral Student

1986-1987

Dr. Chesler completed his M.D./Ph.D. degrees in Physiology and Biophysics from New York University in 1986.  Dr. Chesler went on to complete postdoctoral training under the mentorship of Dr. Kraig at Cornell University from 1986-1987, where he examined how evoked activity and cortical spreading depression shifted intracellular pH in astrocytes.   

Dr. Chesler currently is Professor and Vice Chair for Research in the Department of Neurosurgery, and Professor of Physiology and Neuroscience at New York University School of Medicine.

Publications

Chesler M, Kraig RP (1987) Intracellular pH of astrocytes increases rapidly with cortical stimulation.  Am J Physiol 253:R666-R670.  PubMed

Kraig RP, Chesler M (1988) Dynamics of volatile buffers in brain cells during spreading depression.  In:  Cerebral Hypoxia and Stroke:  Reversible and Irreversible Effects and Their Prevention (Somjen G, ed), pp 279-289.  New York:  Plenum.

Chesler M, Kraig RP (1989) Intracellular pH transients of mammalian astrocytes.  J Neurosci 9:2011-2019.  PubMed

Kraig RP, Chesler M (1990) Astrocytic acidosis in hyperglycemic and complete ischemia.  J Cereb Blood Flow Metab 10:104-114.  PubMed

Chesler M, Chen JC, Kraig RP (1994) Determination of extracellular bicarbonate and carbon dioxide concentrations in brain slices using carbonate and pH-selective microelectrodes.  J Neurosci Methods 53:129-136.  PubMed